Correction for “ Phosphoproteomic characterization of DNA dam - age response in melanoma cells following MEK / PI 3 K dual in - hibition ,
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CELL BIOLOGY Correction for “Phosphoproteomic characterization of DNA damage response in melanoma cells following MEK/PI3K dual inhibition,” by Donald S. Kirkpatrick, Daisy J. Bustos, Taner Dogan, Jocelyn Chan, Lilian Phu, Amy Young, Lori S. Friedman, Marcia Belvin, Qinghua Song, Corey E. Bakalarski, and Klaus P. Hoeflich, which appeared in issue 48, November 26, 2013, of Proc Natl Acad Sci USA (110:19426–19431; first published November 11, 2013; 10.1073/pnas.1309473110). The authors note that Figure 1 appeared incorrectly. The corrected figure and its legend appear below.
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Correction for “ Phosphoproteomic characterization of DNA dam - age response in melanoma cells following MEK / PI 3 K dual in - hibition , ” by Donald
CELL BIOLOGY Correction for “Phosphoproteomic characterization of DNA damage response in melanoma cells following MEK/PI3K dual inhibition,” by Donald S. Kirkpatrick, Daisy J. Bustos, Taner Dogan, Jocelyn Chan, Lilian Phu, Amy Young, Lori S. Friedman, Marcia Belvin, Qinghua Song, Corey E. Bakalarski, and Klaus P. Hoeflich, which appeared in issue 48, November 26, 2013, of Proc Natl Acad Sci USA...
متن کاملCorrection for “ Phosphoproteomic characterization of DNA dam - age response in melanoma cells following MEK / PI 3 K dual in - hibition , ” by
CELL BIOLOGY Correction for “Phosphoproteomic characterization of DNA damage response in melanoma cells following MEK/PI3K dual inhibition,” by Donald S. Kirkpatrick, Daisy J. Bustos, Taner Dogan, Jocelyn Chan, Lilian Phu, Amy Young, Lori S. Friedman, Marcia Belvin, Qinghua Song, Corey E. Bakalarski, and Klaus P. Hoeflich, which appeared in issue 48, November 26, 2013, of Proc Natl Acad Sci USA...
متن کاملCorrection for “ Phosphoproteomic characterization of DNA dam - age response in melanoma cells following MEK / PI 3 K dual in -
CELL BIOLOGY Correction for “Phosphoproteomic characterization of DNA damage response in melanoma cells following MEK/PI3K dual inhibition,” by Donald S. Kirkpatrick, Daisy J. Bustos, Taner Dogan, Jocelyn Chan, Lilian Phu, Amy Young, Lori S. Friedman, Marcia Belvin, Qinghua Song, Corey E. Bakalarski, and Klaus P. Hoeflich, which appeared in issue 48, November 26, 2013, of Proc Natl Acad Sci USA...
متن کاملDual targeting of PI3K and MEK enhances the radiation response of K-RAS mutated non-small cell lung cancer
Despite the significant contribution of radiotherapy to non-small lung cancer (NSCLC), radioresistance still occurs. One of the major radioresistance mechanisms is the hyperactivation of the PI3K/Akt pathway in which Akt facilitates the repair of DNA double-strand breaks (DSBs) through the stimulation of DNA-PKcs. We investigated if targeting PI3K would be a potential approach for enhancing the...
متن کاملRole of Caspases and Reactive Oxygen Species in Rose Bengal-Induced Toxicity in Melanoma Cells
Objective We have previously shown that Rose Bengal (RB) alone, not as a photosensitiser, could induce apoptotic- and non-apoptotic cell death in different melanoma cell lines. To clarify RB-induced toxicity mechanisms, role of caspases and reactive oxygen specious (ROS) were studied in melanoma cells. Material and Methods Human melanoma cell lines, Me 4405 and Sk-Mel-28 were cultured in DM...
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